منابع مشابه
Digital Merkel cell carcinoma.
Merkel cell carcinoma (MCC) is a rare and biologically aggressive neuroendocrine tumour of the skin. Recent analysis of a surveillance, epidemiology and end results program has shown a statistically significant increase of 8% per year in the age-adjusted rates for MCC of the skin over the past 15 years. MCC commonly presents as a painless, rapidly growing, single red or purple cutaneous nodule....
متن کاملMerkel cell carcinoma
BACKGROUND Merkel cell carcinoma (MCC) is an unusual primary neuroendocrine carcinoma of the skin. MCC is a fatal disease, and patients have a poor chance of survival. Moreover, MCC lacks distinguishing clinical features, and thus by the time the diagnosis is made, the tumour usually have metastasized. MCC mainly affects sun-exposed areas of elderly persons. Half of the tumours are located in t...
متن کاملMerkel cell carcinoma.
Merkel cell carcinoma is a rare, highly aggressive neuroendocrine cutaneous neoplasm with a variable clinical presentation. Histologically, it is a predominantly dermal-based lesion composed of monotonous small round cells with scanty cytoplasm, often difficult to differentiate from small round cell tumors, metastatic small cell carcinoma, blastic hematologic malignancies, and melanoma. The mal...
متن کاملMerkel cell carcinoma.
IN 1875, FRIEDRICH Sigmund Merkel (1845-1919) described a unique epidermal nondendritic, nonkeratinocyte cell, which he called a tactile cell (Tastzelle). This cell, now bearing his name, was thought to be a primary touch receptor. Merkel cells are now generally believed to be primary neural cells, found as single cells within the basal layer of the epidermis or grouped together as a component ...
متن کاملMerkel cell carcinoma.
Merkel cell carcinoma (MCC) is a rare yet highly aggressive tumour of the skin. While the dangers of other skin cancers like malignant melanoma are ingrained in most physicians’ minds—with the changing or atypical nevus often inciting an urgent biopsy—MCC remains an unfamiliar and neglected disease. Yet, the annual incidence of MCC is rising more quickly than that of melanoma, at 8% annually, a...
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ژورنال
عنوان ژورنال: HAND
سال: 2016
ISSN: 1558-9447,1558-9455
DOI: 10.1177/1558944715616098